Richets is not the deposit of mineral in the skeletal tissue and is the retardation of skeletal growth in growing animals. In the skeletal disease such as rickets, vitamin D was known the most effective element.
The purpose of this study was to investigate mineral changes induced by rachitogenic diet No. 2, which was high in calcium but low in phosphorus and deficient in vitamin D upon the dental structures and. mandibular bone of rats.
For this study, 48 albino rats were used and divided into two groups. While 24 rats of experimental group were maintained rachitogenic diet, 24 rats of control group were maintained normal diet for experimental period. For observation, animals were killed at 7 days intervals during the 42 days period and obtained specimen of teeth and mandibular bone. After both materials were powdered, Ca content determined by atomic absorption spectrophotometer (Shiimadju Co, Flame Emission Spectrophotometer : AA640 -1-8) and P content determined by UV spectrophotometer (Bausch and Lomb, Spectrophotometer 21).
The results were as follows :
1. The Ca content in incisor of control group rose from 19.0 96 of dry weight in 7 days to 19. 8 96 in 42 days while that of experimental group fell from 18. 6 96 in 7 days to 17. 8 96 in 42 days.
2. The P content in incisor of control group rose from 9. 8 96 dry weight in 7 days to 10. 7 96 in 42 days while that of experimental group fell from 9. 6 96 in 7 days to 8. 8 96 in 42 days.
3. The Ca content in molar of control group rose from 19. 0 96 of dry weight in 7 days to 19. 8 96 in 42 days while that of experimental group fell from 18. 8 96 in 7 days to 18. 3 96 in 42 days.
4. The P content in molar of control group rose from 10. 0 % of dry weight in 7 days to 10. 7 96 in 42 days while that of experimental group fell from 9. 9 % in 7 days to 9. 4 % in 42 days.
5. The Ca content in mandibular bone of control group rose from 14. 2 ´ of dry weight in 7 days to 15. 0 % in 42 days while that of experimental group fell from 14.0 in 7 days to 11. 5 % in 42 days.
6. The P content in mandibular bone of control group rose from 7.5 % of dry weight in 7 days to 8. 7 96 in 42 days while that of experimental group 7. 4 96 in 7 days to 6. 2 96 in 42 days.
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